The Falcons were already eight tries up when the half time whistle blew at 54-7, after carving the Italians up in some style.
Prop Robbie Morris, who had helped himself to two last week, was first over after a pick and go from a short range ruck.
Mathew Tait, back from England Sevens duty in Dubai and South Africa, doubled the lead with a well-crafted score in the left corner after a 70-metre run from Walder and a deft offload from the fullback.
It was Walder himself who grabbed the third when a five-metre scrum saw James Grindal draw the defence and feed him for the score, Walder dummying the last man.
With Newcastle totally dominant upfront openside flanker Cory Harris utilised a powerful rolling maul from a Grimes line out take in the left corner to touch down, racking up the bonus point before the 20-minute mark.
The biggest cheer of the day, albeit it an ironic one, came when L'Aquila finally got on the score sheet, as Tait's intercepted pass on half way saw left wing Pierluigi Gentile sprint in for a try, converted by fly half Hostie.
Normal service was resumed within two minutes when centre Jamie Noon crossed the line for the Falcons' fifth after a huge scrum on the 22 fed Mayerhofler, who dummied well before offloading to Noon from close range.
It was Mayerhofler himself who was next to score after a dummy and break from fly half Flood put the Kiwi in, with the L'Aquila defence in tatters.
Italian fly half Hostie tried tosend his side in to double figures with a penalty for midfield offside, but his effort drifted left of the uprights as Newcastle continued to bombard the try line.
There was time for twomore before the interval, including a first Falcons try for Owen Finegan as he powered over from short range, while Grindal, who had created so many of the tries,finally gotin on the act with one of his own for a 47-point interval lead.
There was no let-up as the second half started, with James Hoyle crossing in the left corner after the forwards had sucked numbers in to the maul in the opposite side of the field.
L'Aquila finally got in to the Newcastle 22 after a penalty produced a five-metre line out down the right hand side, but they were denied a score as Noon dumped fly half Hostie and Flood touched down a grubber in to the dead ball area.
Replacement hooker Matt Thompson benefited from bulldozing running by Noon to score the tenth as he dummied and went in from five metres down the left following a superb break from the centre.
The departure of Tait midway through the second half saw Matthew Burke enter proceedings, with the ensuing backline reshuffle seeing Walder switch to flyhalf, Flood to inside centre, Mayerhofler to outside and Noon to the wing as Burke slotted in to his accustomed fullback berth.
The eleventh was similarly route one as replacement flanker McCarthy powered through two tackles to barge a path to the try line, while a cross field kick from Walder almost produced a try after breaks from Mayerhofler and Hoyle.
As if the visitors' task wasnot hard enough with 15 men, they were reduced to 14 when right wing Roberto Mariani was sin binned foran offence at a ruck on his own 22.
Woods almost put Hoyle in as the scoring dried up for a spell, and the clinical edge of earlier in the game saw balls hit the ground with the try line beckoning.
An attacking line out ten metres out saw the momentary deadlock finally broken as McCarthy rose well, fed Jonny Williams on the peel and Paoletti crashed in on a straightening support line for his first Falcons try.
Walder jinked 70 metres on a scorching run, only for his offload five metres from the line to find the deck, but the line out was again the Falcons' saviour as Thompson grabbed a second from an unstoppable 15-metre rolling maul.
But the Italians were not giving up, and a speculative upfield kick from fullback Martin Acuna produced a second try as Grindal and Burke went for the same ball - Hostie converting.
Persistent attack from the hosts, however, saw McCarthy grab a second from an inside ball by Burke, before referee Andy Ireland brought an emphatic home win to an end with the final whistle.
Newcastle Falcons:
Tries: Morris, Tait, Walder, Harris, Noon, Mayerhofler, Finegan, Grindal, Hoyle, Thompson 2, McCarthy 2, Paoletti
Cons: Walder 10
L'Aquila:
Tries: Gentile, Acuna
Cons: Hostiè 2
Newcastle Falcons:
15 Dave Walder
14 James Hoyle
13 Jamie Noon
12 Mark Mayerhofler
11 Mathew Tait (Matthew Burke, 59)
10 Toby Flood
9 James Grindal
1 Jonny Williams
2 Andy Long (Matt Thompson, 40)
3 Robbie Morris (Tino Paoletti, 40)
4 Andy Perry (Geoff Parling, 52)
5 Stuart Grimes
6 Owen Finegan (Mike McCarthy, 40)
7 Cory Harris (Ben Woods, 52)
8 Colin Charvis (captain, Andy Buist, 40)
Replacements:
16 Tino Paoletti
17 Matt Thompson
18 Geoff Parling
19 Andy Buist
20 Mike McCarthy
21 Ben Woods
22 Matthew Burke
L'Aquila:
15 Martin Acuna
14 Roberto Mariani
13 Nicolas Canavosio
12 Marco Rosa
11 Peirluigi Gentile
10 Francesco Hostiè
9 Juan Cruz Legora
1 Luigi Milani
2 Antonello Comperti
3 Colin Quigley
4 Juan Jose Rapetti
5 Agustin Cavalieri
6 Andrea Tagliavento
7 Aldo Birchall
8 Pierpaolo Rotilio
Replacements:
16 Massimo Alfonsetti
17 Flavio Tripodi
18 Stefano Ciancarella
19 Fabrizio Parisse
20 Andrea Brancoli
21 Santiago Monteagudo
22 Francesco Zullo
Referee: Andy Ireland
Attendance: 5,216
