Radwan and Blamire selected for Tonga clash
The 23-year-old scored a hat-trick on his debut against Canada over the summer, and is joined in the match-day 23 by club-mate Jamie Blamire.
The Cumbrian has scored four tries in his two England caps to date, having crossed the line on his debut against the USA before grabbing a hat-trick against Canada.
Falcons prop Trevor Davison is not among the match-day 23 despite having trained all week with the national side, while Falcons back-row Callum Chick is available for club duty after being released from the England squad on Tuesday night.
Saturday’s game is a 3.15pm kick-off, and is being shown live in the UK on Prime Video.
Meanwhile, Falcons lock Marco Fuser starts for Italy as they open their autumn campaign against New Zealand in Rome.
The Stadio Olimpico clash is a 1pm UK-time kick-off on Saturday, and is being shown in the UK on Prime Video.
Newcastle wing Mateo Carreras makes his first start for Argentina as they to face France in Paris on Saturday, having won his first two caps from the bench against Australia in the recent Rugby Championship.
Saturday’s game kicks off at 8pm UK time, and is also live on Prime Video.